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Institut Dermed Introduces New Chromabright Serum

30 August 2011 No Comment


Chemist’s Clinical Ingredient Research

Introducing…
CHROMABRIGHT™
A CUTTING-EDGE MOLECULE
FOR A RADIANT SKIN TONE
and a new active for safe
skin brightening

CHROMABRIGHT™, a new patented molecule for skin brightening:
  • Inhibits human tyrosinase activity in vitro
  • Higher melanogenesis inhibition than Arbutin, MAP and Kojic Acid
  • Same depigmenting activity than Hydroquinone without cytotoxicity
  • Proven in vivo brightening efficacy
  • High stability in formulations
  • High solubility in oils
  • Impeccable safety profile

Primary human melanocytes (hemn-dp) cell cultures were used to compare the skin lightening performance of Hydroquinone, Arbutin, Magnesium Ascorbyl Phosphate (MAP) and Kojic Acid to that of CHROMABRIGHT™ at the same concentration (10μM) for a period of 20 days. As the graph above demonstrates, CHROMABRIGHT™ exhibited a better depigmenting effect than MAP, Kojic Acid and Arbutin, and a had similar efficacy to Hydroquonone.

  • Unlike other depigmenting agents that can cause photo irritation, preventing UV-induced skin damage, CHROMABRIGHT™ has a photoprotective effect.


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